History I Honors22 February two hundred9In America in the 1950s, spend was a sentence of despair and c at a metrern for most p bents; this was the time when children by the thousands became glide by with the incapacitating disease acute anterior infantile paralysismyelitismyelitismyelitis. fortuitously this cultism was lifted everto a greater extent when it was announced that Dr. Jonas Salk had transgressed a vaccinum against towards this disease. Salk became population-famous oernight, and his un extending was the result of many social classs of scrupulous research. Jonas Salk was born in refreshful York City. His p bents were immigrants who lacked a formal education, entirely were determined to depend their children succeed and encour epochd them to reading hard. Jonas Salk was the freshman member of his family to go to college; he entered the City College of New York intending to ask uprightness, but soon became intrigued by medical examination sci ence. eyepatch in college he met his here afterwards wife, Donna Lindsay, whom he matrimonial on June 9, 1939. They had three children: Peter, Darrell, and Jonathan. In 1968, they divorced, and in 1970 Salk married FranÃ§oise Gilot, the agent mistress of Pablo Picasso. While attending medical school at New York University, Salk was invited to spend a year researching in grippeenza. The computer computer virus that ca intentions flu had only recently been discovered and Salk waseager to check into if the virus could be deprived of its ability to infect, but even give immunity to the illness. Salk succeeded in this attempt, which became the basis of his later achievement on infantile paralysis. After completing medical school and his internship, Salk returned to the cogitation of honor of influenza, the flu virus. knowledge domain War II had begun, and public wellness experts feargond a replay of the flu epidemic that had killed jillions in the inflame up of Wor ld War I. The development of vaccinums co! rrespondled the spread of flu after the war and the epidemic of 1919 did non recur. In 1947, Salk pass judgment an appellation to the University Of Pittsburgh Medical School. While working there, with the subject field Foundation for immature Paralysis, Salk saw an opportunity to develop a vaccinum against infantile paralysismyelitismyelitis; he devoted himself to this work for the attached eight years. acute anterior poliomyelitis is a exceedingly infectious disease caused by a virus. It invades the nervous ashes and whoremaster cause total palsy in a matter of hours. This incurable disease gage strike at any age but principally affects children under 5 years of age. One in 200 infections led to irreversible paralysis (usually in the legs). Among those paralyzed, 5% to 10% would die when their ventilation muscles become immobilized. The virus enters the body by contaminated food, unclean fingers or water tainted with sewage. The virus attaches to receptors on the enteral walls; this is where it gets into the bloodstream. It then invades the CNS (central nervous system) banquet along strikingness fibers. As it multiplies the virus destroys nerve cells, get neurons, which are the neurons need to activate muscles. These nerve cells cannot be regenerated and therefore, the alter muscles no semipermanent function. In the most severe cases, the polio virus attacks the force neurons of the brain stem, reducing breathing capableness and causing problem in swallowing and speaking. This is known as bulbar polio and can result in death without respiratory support. The fight against polio didn?t actually begin until 1938 when the National Foundation for immature Paralysis was discovered. Basil OConnor, the former law partner of hot seat Franklin D. Roosevelt, Americas most distinguished polio victim, began it. withal that same year, the archetypical March of Dimes fundraising program was set up, radio receiver networks offered u nembellished 30-second slots for promotion. Audience ! members were asked to send in a dime root to the White House. They received 2,680,000 letters within days a few days. As the fear of polio increased one after another year, funds to fight it increased from $1.8 gazillion to $67 million by 1955. Research continued during those years, but, O?Neill writes, Everything scientists believed about polio at first was wrong, leading them down many cover alleys. Furthermore, most researchers were experimenting with highly dangerous conk vaccinums. In oneness test six children were killed and three left crippled.Although there is ease not a cure for polio to this day, it has been brought under sway by immunization. In 1955 Salks years of research paid off, the soft trials of the polio vaccine effectively protected the subject from the polio virus. When refreshings of the discovery was make public on April 12, 1955; Salk was hailed as a miracle worker. He further endeared himself to the public by refusing to apparent(a) the vaccine. He had no desire to profit personally from the discovery, but merely wished to essay the vaccine disseminated as widely as possible. Salks vaccine was tranquil of killed polio virus, which retained the ability to protect without running the lay on the line of infecting the patient. A few years later, a vaccine madefrom live polio virus was developed, which could be administered orally, mend Salks vaccine undeniable injection. Also there was several(prenominal) curtilage that the killed vaccine failed to in all immunize the patient. In the U.S., public health authorities choose to distribute the live oral vaccine instead of Salks. regrettably the preparation of the live virus septic some patients with the disease, alternatively than immunizing them.
Since the introduction of the original vaccine, the few new cases of polio describe in the United States were probably caused by the live vaccine which was intended to prevent them. In countries where Jonas Salks vaccine still has remained in use, the disease has been nearly eradicated. Beginning in the early 1980?s, Salk in addition engaged in research to develop a vaccine for another, more recent plague, AIDS. To further this research, he co-founded The Immune resolution Corporation with Kevin Kimberlin, to search for a vaccine, and they also patented Remune, an immune-based therapy. It has not yet been evaluated by the U.S Food and drug Administration (FDA) for use by people living with HIV. Unfortunately Salk died at age 81 due to heart disaster; before a successful vaccine was found, and although many advances were made in treating AIDS, ?The world still waited for the miracle vaccine the conqueror of polio had sought,? wrote historian Alan Axelrod. Fortunately before his death, Salk founded the Jonas Salk Institute for Biological Studies in 1963; it was an innovative inwardness for medical and scientific research. Jonas Salk also began to make known books, some even written with sensation or more of his sons, who are also medicalscientists. Salks published books include Man Unfolding, The choice of the Wisest, World Population and Human Values: A New Reality, and name of Reality. During his life time Jonas Salk accumulated many honors one of which was presented to him in 1977. It was the chairmanial Medal of Freedom and was given to him by President Jimmy Carter, and with the following statement accompanying the medallion:?Because of reinstate Jonas E. Salk, our country is free from the cruel epidemics of poliomyelitis that once in love almost yearly. Because of his tireless work, untold hundreds of thousands who might take over been crippled are sound in body today. These a! re Doctor Salk?s true honors and there is no government agency to add to them. This Medal of Freedom can only tell our gratitude, and our deepest thanks.?Thanks to Jonas Salk in 2008 researchers found only 4 countries in the world which remain polio-endemic, this is down from more than 125 countries in 1988. The remaining countries are Afghanistan, India, Nigeria and Pakistan. Since 1988 the number of polio cases has fallen by over 99%. Works CitedI.www.faqs.org, http://www.faqs.org/health/bios/14/Jonas-Salk.htmlII.www.time.com, http://www.time.com/time/time100/scientist/profile/salk03.htmlIII.www.kidshealth.org, http://kidshealth.org/parent/infections/bacterial_viral/polio.html If you extremity to get a to the full essay, order it on our website: OrderCustomPaper.com
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